Thursday, March 17, 2011

Re: [fast5] Re: Hello! New Here - Question..(The Beans Trick).

On Thu, Mar 17, 2011 at 7:20 PM, Barnaby Walker <barnabywalker@gmail.com> wrote:

Insulin is what Taubes, Groves, Eades all boil down to.

http://www.youtube.com/watch?v=Akz9B-zMS-4

Fasting lowers Insulin.

Low Carbs lower Insulin.

If you eat Grain, it's like tying your hands behind your back as far as Insulin creation.

Insulin resistance also goes up when you get a lot of iron in your system. Not much of a problem for younger women, but it is a problem for guys. Human beings tend to over-absorb heme iron iron (but not vegetable iron). Enter the humble bean, or brown rice. Not only does it slow down absorption, but it blocks the iron in the meal from being absorbed. There is a nice paper on this at Medscape (it's free, but you have to register):

Cross-Talk Between Iron Metabolism and Diabetes: Clinical and Therapeutical Implications of Iron Depletion

http://www.medscape.com/viewarticle/439591_6

A. Insulin Influences Iron Metabolism
Insulin is an anabolic hormone that stimulates the cellular uptake of many nutrients, including hexoses, amino acids, cations and anions. Intestinal absorption of nonheme iron is tightly regulated in keeping with the body requirements, and absorption of iron is minimal when body iron stores are normal. Absorption of heme iron (largely provided by red meat in western countries) does not appear to be dependent on body iron content. In the steady state, circulating iron is bound to transferrin and is taken up from the blood by a high-affinity specific transferrin receptor. The transferrin-receptor complex is internalized by endocytosis and released into a nonacidic cellular compartment, where it can be used in the synthesis of essential cellular components. Insulin is known to cause a rapid and marked stimulation of iron uptake by fat cells, redistributing transferrin receptors from an intracellular membrane compartment to the cell surface.^[45] Insulin is also responsible for the increased ferritin synthesis in cultured rat glioma cells.^[46] Importantly, transferrin receptors have been shown to colocalize with insulin-responsive glucose transporters and insulin-like growth factor II receptors in the microsomal membranes of cultured adypocytes, suggesting that regulation of iron uptake by insulin occurs in parallel with its effects on glucose transport.

B. Iron Influences Glucose Metabolism

Reciprocally, iron influences insulin action. Iron interferes with insulin inhibition of glucose production by the liver. Hepatic extraction and metabolism of insulin is reduced with increasing iron stores, leading to peripheral hyperinsulinemia.^[48] In fact, the initial and most common abnormality seen in iron overload conditions is liver insulin resistance.^[49]There is some evidence that iron overload also affects skeletal muscle,^[50] the main effector of insulin action.

I think one of the reasons Fast-5 works might be that it allows the body to do "housecleaning" between meals, including the shedding of gut cells that are the main iron stores? I dunno. But if you are worried about insulin levels, it's a good idea to eat some iron-blocking food along with whatever else you are eating. These include things like beans, tea, chili peppers.

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